Medialab Prado is the coolest place to work, to collaborate, to do workshops, to participate in events and conferences. They are the nicest people in the planet doing such interesting programs. My favorite is Interactivos. It is also a good place to meet new friends and go afterwards for beers in the bars around Lavapies, a district full of art galleries and Museums.
Spanish artist Jaime Hayon is sometimes called Almodóvar of design. So if you like "Kika", colours, Spanish culture and dreamy aestetics, you must visit Barceló Torre de Madrid and stay there for a night or just have a drink in a golden bar.
A bar and bookshop to enjoy a glass of wine while reading a book or to read a book while drinking a glass of wine. They show a careful selection of contemporary literature and artworks downstairs, from where you can spy on the people upstairs because the ceiling is made of glass.
This is a fabulous Hotel called Silken Puerta América, where each floor is designed by a different architect. It is open for public visiting. This year the Hotel was hosting the art fair Just Madrid and I was totally amazed by the first floor design of my favorite architect Zaha Hadid.