Matadero is a contemporary creation center, a charming place to go at night to see the concerts and architectural lights. It always has an interesting program going on.
Good place to go for a quick healthy lunch or dinner, you can choose from a variety of paleo, vegan and vegetarian dishes. They also have a great organic coffee too!
Reina Sofia museum is always a good idea. And it's never enough of Picasso's Guernica as well as the other modern art gems. Save some hours for visiting and then look round the corner and have some wine at NuBel.