After long hours at Reina Sofia museum time for going to Outer Space. It's called NuBel and it makes you wonderfully dizzy. Or, better, go there just before the museum - drink some wine and go to admire Guernica in 3D.
Secret cocktail bar set in a 17th century library. From the outside, it looks like an old charming bonsai shop. You can only access with reservation. To make the experience even more exclusive, visitors must enter a secret code in a small and discreet door.
Medialab Prado is the coolest place to work, to collaborate, to do workshops, to participate in events and conferences. They are the nicest people in the planet doing such interesting programs. My favorite is Interactivos. It is also a good place to meet new friends and go afterwards for beers in the bars around Lavapies, a district full of art galleries and Museums.
Good place to go for a quick healthy lunch or dinner, you can choose from a variety of paleo, vegan and vegetarian dishes. They also have a great organic coffee too!