Medialab Prado is the coolest place to work, to collaborate, to do workshops, to participate in events and conferences. They are the nicest people in the planet doing such interesting programs. My favorite is Interactivos. It is also a good place to meet new friends and go afterwards for beers in the bars around Lavapies, a district full of art galleries and Museums.
Reina Sofia museum is always a good idea. And it's never enough of Picasso's Guernica as well as the other modern art gems. Save some hours for visiting and then look round the corner and have some wine at NuBel.
Matadero is a contemporary creation center, a charming place to go at night to see the concerts and architectural lights. It always has an interesting program going on.
Though you might say the city is full of colors, from Velazquez's tones of greys to Miro's vivid strokes and shapes. From Goya's darkness to Picasso's blues, Rastro's potency and variety of people and fabrics, or even shop windows for tourists full of Sevillanas and colorful magnets - the biggest canvas is above all of us. It's hard to beat the intense blue of Madrid's sky.
I have no idea if Giotto has been here, but I'm pretty sure he was inspired by Madrid's sky to paint Padua's chapel's ceiling.
The smoothest blue of Madrid's sky lies in contrast with the dryness and ocre buildings and landscape gives me torticollis.
The colors may vary from mediterranean sea, Yves Klein Blue and Pantone 293C. It doesn't matter how it's defined - it is, for me, a boost of cheerfulness in any place and mindset I find myself in. I won't be able to touch or reach the blueness of this sky, but it touches me. Deeply. And I happily allow it.