In the Mission, now as terminally hip as it was formally poor, the St Francis is a greasy good time since 1918. Stuck beautifully in the 50's both aesthetically and menu wise it's Americana in a bun. Dig in.
You have a lot of hills to choose from in San Francisco but in my opinion the best (and most varied) views are from Bernal Hill. Bonus: from my kitchen table I can watch tiny blobs moving around on this hill-- slow blobs are people, fast blobs are dogs.
Murals! where? everywhere! walls, streets, signs, windows. keep your eyes peeled. I walk a lot in San Francisco and always seem to find new murals in the least expected places. They are a constant source of inspiration, and make me wish I could paint worth a damn.