As Jim Jarmusch put it in the documentary Blank City, the address is roughly between Bowery, Avenue B, 14th Street and Houston. This area of the city is steeped in art, film, and music history; so many hugely influential artists, film makers, and musicians still live and work here. For such a small area, I think it's had more concentrated influence on contemporary art and culture than anywhere else.

You need to make a reservation for L'Artusi years in advance... or at least the week before, if you try a walk-in then ask to be seated at the bar, as always in New York that is the best seats at any of my favorites restaurants.

The best, coziest place for a burger! 

The Bronx Botanical Garden is a place my father and I have been going to since I was a child. Here's a photograph I took of him here. It has hundreds of species of trees and flowers. Sitting in the middle of the Bronx, it's most recognizable as a green oasis from the grays and concrete of city life. 

Taco Chulo is a great Mexican restaurant that has a good selection of tacos and burritos and of course has interesting blends of margaritas. I probably eat here at least once every other week.