Taco Chulo is a great Mexican restaurant that has a good selection of tacos and burritos and of course has interesting blends of margaritas. I probably eat here at least once every other week.
ANTHOM’s gallery-like store on Mercer Street is all about presentation, and their selection of pieces from designers like Lady Artigas, Mari Giudicelli, Yune Ho, Marni, and Suzanne Rae is displayed with an eye for design.
Chinatown in general, I've lived in chinatown on and off for my entire time in New York and i never tire of it’s textures, smells, artificial lighting and grime. There's some amazing things to happen upon there as you trek about your way, a true city experience. Love this little culture shop Aeon, gems of records, art and ephemera tucked away like most good things are.
I'm a huge Japanophile: if there's one other place I'd like to live, it's Tokyo. I must have been there seven or eight times, most recently just after the Tohoku earthquake and tsunami. Anyway, EN is a gem on Hudson Street, serving real Japanese cuisine. It turns out that EN is a chain in Japan; there are a lot of branches making lovely bosky food in cosy neighbourhood locations. But their New York incarnation is grand in scale and ambition, with solid, warm interiors (not unlike if the Whitney were a Japanese restaurant, oddly) - a remarkable hybrid of this city, and the other one that I'd love to live in.