As Jim Jarmusch put it in the documentary Blank City, the address is roughly between Bowery, Avenue B, 14th Street and Houston. This area of the city is steeped in art, film, and music history; so many hugely influential artists, film makers, and musicians still live and work here. For such a small area, I think it's had more concentrated influence on contemporary art and culture than anywhere else.
Within an couple hours' drive of NYC, you can find lots of sleepy seaside towns. Not only can you get your soft ice cream and salt water taffy on, but you can still spot cool, hand-lettered signs and other relics of a past generation's amusements.
The Home Depot is one of the first things I saw when the taxi brought me at the place where I live now in NYC. I am renting a room in an old feather factory, which the owner build into a very cozy loft with rooms, common places and studios over the last 12 years. The Home Depot is a massive construction store, one of the leading ones in the US if you can say something like that about construction stores...You ll find them everywhere in the states as well as in my backyard and you can even follow them on Facebook. In general everybody in Bed Stuy complains about the Home Depot, because the employees are grumpy, lazy and never know anything when you ask them for something.