The second coffee shop has to be Kaffeine. Having only recently come across this one, I was certainly impressed and they may even have the best coffee I've had, since a short stay in Portland, Oregon.
Tucked away down a cobbled alley behind Russell Square Station, The Horse Hospital, a converted stable, is a unique and totally independent arts space specialising in underground and experimental media. The gallery space itself (known as The Chamber of Pop Culture) houses unusual exhibitions, film screenings and other events.
By far the best bagels in London, they are open 24 hours and being just down the road from my flat a bit too local. It is run by a man called Mr Sammy, who doesn't muck about with portion size. It is well worth a visit especially for their smoked salmon and cream cheese speciality.