Seasonal salads, sweet and savory treats, and great coffee. It's probably my most common lunch spot when I work from home and they also offer catering if I'm too nervous to cook but want it to feel homemade.
As Jim Jarmusch put it in the documentary Blank City, the address is roughly between Bowery, Avenue B, 14th Street and Houston. This area of the city is steeped in art, film, and music history; so many hugely influential artists, film makers, and musicians still live and work here. For such a small area, I think it's had more concentrated influence on contemporary art and culture than anywhere else.