The Chelsea Market is filled with great restaurants and speciality food stores and pop up shops. I love stopping in and getting a gourmet grilled cheese from Lucy's Whey or a healthy juice from raw food restaurant One Lucky Duck, while shopping for dinner ingredients at the Italian market Buon Italia. For a great sit down restaurant, I love The Green Table, which serves great farm to table food.
Occasionally I'll look at the Manhattan skyline and wonder what it was like in 1931 when people around the world were saying, "Holy shit, did you hear what they just built in New York?" Just get up there and trip out about humanity. And be sure to keep an eye out for the unmarked locked door guarding a set of stairs leading to a hidden terrace that was originally designed as a fucking docking station for zeppelins.